Free radicals and oxidative stress can accelerate the aging process. Help slow it down with resveratrol…nature’s turbocharged antioxidant. MX Resveratrol Complex even contains the same amount of resveratrol as 13 glasses of red wine.

Supplement Facts:

Resveratrol (from Japanese Knotweed)	25mg
Spirulina	47.5mg
Total Polyphenols:made up from	100mg
Polyphenols (from Sustainable NZ Pine bark)	30mg
Polyphenols (from NZ grape seed extract)	30mg
Polyphenols (from Green Tea)	40mg

Cautions
Because resveratrol demonstrates antiplatelet (blood-thinning) activity, individuals taking blood thinners are recommended to consult a physician before taking resveratrol. Also consult your healthcare professional if on prescription medication, or pregnant or breastfeeding.

What is your recommended dosage?
We recommend 2 tablets a day.

How will I benefit from MX Reservatrol Complex?
Maxalife Resveratrol Complex will aid in cholestrol balance and has been linked to lowering blood glucose. The high antioxidant concentration minimises oxidative stress and can help the effect of conditions related to aging.

Will I feel any ill effects?
It is not a normal response to feel any untoward symptoms, if, however, you do feel a little queasy after, then just take them with a meal.

Can I take MX Reservatrol Complex with other medications?
Because resveratrol demonstrates antiplatelet (blood-thinning) activity, individuals taking blood thinners are recommended to consult a physician before taking resveratrol. Also consult your healthcare professional if on prescription medication, or pregnant or breastfeeding.

How can I improve my health and well being in other ways?
It is always important to make sure you eat a good, balanced diet and to incorporate moderate exercise into you schedule.

What if I have questions regarding your products?
Please feel free to send us an email, we will answer your questions, it is always good to know what our customers wish to be informed about, just go to our contact us page.

 

Resveratrol, a natural product derived from grape, exhibits antiestrogenic activity and inhibits the growth of human breast cancer cells

Runqing Lu1, Ginette Serrero1,2,

Abstract

Resveratrol is a natural phytoalexin compound found in grapes and other food products. In this study, the effect of resveratrol on the growth of human breast cancer cells was examined. Results show that resveratrol inhibits the growth of estrogen receptor(ER)-positive MCF-7 cells in a dose-dependent fashion. Detailed studies with MCF-7 cells demonstrate that resveratrol antagonized the growth-promoting effect of 17-ß-estradiol (E2) in a dose-dependent fashion at both the cellular (cell growth) and the molecular (gene activation) levels. At 5 × 10-6 M, resveratrol abolished the growth-stimulatory effect mediated by concentrations of E2 up to 10-9 M. The antiestrogenic effect of resveratrol could be observed at a concentration of 10-6 M and above. The antiestrogenic effect of resveratrol was also demonstrated at the molecular level. Resveratrol in a dose-dependent fashion antagonized the stimulation by E2 of progesterone receptor gene expression in MCF-7 cells. Moreover, expression of transforming growth factor-a and insulin-like growth factor I receptor mRNA was inhibited while the expression of transforming growth factor ß2 mRNA was significantly elevated in MCF-7 cells cultivated in the presence of resveratrol (10-5 M). In summary, our results show that resveratrol, a partial ER agonist itself, acts as an ER antagonist in the presence of estrogen leading to inhibition of human breast cancer cells. J. Cell. Physiol. 179:297–304, 1999. © 1999 Wiley-Liss, Inc.

Resveratrol Ameliorates the Deleterious Effect of Severe Acute Pancreatitis.

Jha RK, Ma Q, Lei Z, Sha H..

Department of Surgery, First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China, rajivxjtu@gmail.com.

Abstract

Resveratrol RES) is a traditional Chinese herbal medicine having anti-inflammatory properties. We sought to explore the role of RES in intestinal injury during severe acute pancreatitis (SAP) in a rat model study. For this purpose, RES-treated and sham-operated (SO) SAP rat models were established, and SAP was induced in rats by injecting 4% sodium taurocholate into the biliary-pancreatic duct. In the RES group, RES was infused intravenously immediately after the SAP induction in rats; SO group served as controls. Histopathological analysis, determination of tissue levels of superoxide dismutase (SOD) and malondialdehyde (MDA) and serum levels of TNF-a as well as ICAM-1 and VCAM-1 expression were carried out at 3, 6, and 12h following SAP induction. The data show that following SAP induction, SOD levels decreased and MDA levels increased along with ICAM-1 and VCAM-1 expression in the intestine. Serum TNF-a levels increased in the SAP group. Importantly, RES treatment significantly reversed all the pathological changes. In conclusion, this study confirmed the anti-inflammatory properties of RES and demonstrated the prevention of injury to the intestinal barrier in the rat SAP model.

PMID: 22042732 [PubMed - as supplied by publisher]

Antifungal Activity of Resveratrol against Botrytis cinerea Is Improved Using 2-Furyl Derivatives.

Caruso F, Mendoza L, Castro P, Cotoras M, Aguirre M, Matsuhiro B, Isaacs M, Rossi M, Viglianti A, Antonioletti R.

Istituto di Chimica Biomolecolare, Consiglio Nazionale delle Ricerche, University of Rome, Istituto Chimico, Rome, Italy.

Abstract

The antifungal effect of three furyl compounds closely related to resveratrol, (E)-3,4,5-trimethoxy-ß-(2-furyl)-styrene (1), (E)-4-methoxy-ß-(2-furyl)-styrene (2) and (E)-3,5-dimethoxy-ß-(2-furyl)-styrene (3) against Botrytis cinerea was analyzed. The inhibitory effect, at 100 µg ml(-1) of compounds 1, 2, 3 and resveratrol on conidia germination, was determined to be about 70%, while at the same concentration pterostilbene (a dimethoxyl derivative of resveratrol) produced complete inhibition. The title compounds were more fungitoxic towards in vitro mycelial growth than resveratrol and pterostilbene. Compound 3 was the most active and a potential explanation of this feature is given using density functional theory (DFT) calculations on the demethoxylation/demethylation process. Compound 3 was further evaluated for its effects on laccase production, oxygen consumption and membrane integrity of B. cinerea. An increase of the laccase activity was observed in the presence of compound 3 and, using Sytox Green nucleic acid stain, it was demonstrated that this compound altered B. cinerea membrane. Finally, compound 3 partially affected conidia respiration.

PMID: 22022392 [PubMed - in process] PMCID: PMC3191159